Stanovení železa v biologických materiálech metodou ICP-DRC-MS

Abstrakt

Determination of iron by the title method is complicated by spectral interferences of polyatomic ions, in particular ArO⁺ and CaO⁺. This work was focused on the possibility of reducing the interference using a dynamic reaction cell (DRC). The cell was pressurized with He (collision gas) and methane (reaction gas). Settings of DRC were optimized to achieve maximal efficiency of elimination of interferences. The determination of ⁵⁶Fe and ⁵⁷Fe was tested and the limit of detection and linearity of calibration curves were determined. The accuracy of the method was verified by analysis of a certified reference material.